Biosynthesis of fatty acids and biosurfactants by the yeast Yarrowia lipolytica with emphasis on metabolic networks and bioinformatics

: Yarrowia lipolytica is a haploid, aerobic, and non-pathogenic yeast with biotechnological importance due to its lipolytic proteolytic properties. It capable of producing lipases, biosurfactants, long chain fatty acids, also metabolizing different types carbon sources such as hydrocarbons. Besides, Y. receives attention ability produce organic acids. In this review, we explore metabolic abilities acids for the fine chemical industry (fatty acid-derived bio-based compounds) important food pharmaceutical industries bioremediation. With accelerated advance ‘omics’ technologies, e.g., genomics, proteomics, metabolomics, genetic engineering, combined bioinformatics, substantial data are increasingly available, allowing optimize applications microorganism. Thus, review covers biosynthesis biosurfactants by lipolytica, exploring current knowledge how regulates accumulation these compounds role cutting-edge technologies in understanding engineering metabolism. Topics be addressed include channeling into lipid metabolism, nitrogen other growth factors metabolism target compounds, besides acid transport, regulatory networks, computational models available lipolytica.